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Some charities are much more cost-effective than other charities, which means that they can save many more lives with the same amount of money. Yet most donations do not go to the most effective charities.

This study (from, among others, @SpencrGreenberg) found that participants donated more to the most effective charity, and less to an average charity, when informed about this large difference in cost-effectiveness.

https://www.cambridge.org/core/journals/judgment-and-decision-making/article/donors-vastly-underestimate-differences-in-charities-effectiveness/B7455AC3708440D10454BA2FD6B3F332